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The Physical Precursors for the Ms 8.7 and Ms 8.5 Earthquakes in Indian Ocean

Sun Wei,Sun Xiaoming

Strategic Study of CAE 2008, Volume 10, Issue 2,   Pages 14-25

Abstract:

The precursors-the gestation process and the signal of impending earthquake of the Indian Ocean Earthquakeof Ms 8-7 are recorded,with a serious of specially made monitoring instruments,including instrumentsthat there are great differences for the stress in crust between before and after the eart hquake of Ms8-7 and that of Ms 8-5.8-7 earthquake.

Keywords： Ms 8-7 and Ms 8-5 earthquake in Indian Ocean     earthquqke precursor     signal of impending earthquake     tsunami    

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Single and joint effects of HHCB and cadmium on zebrafish (

Lei ZHANG, Jing AN, Qixing ZHOU

Frontiers of Environmental Science & Engineering 2012, Volume 6, Issue 3,   Pages 360-372 doi: 10.1007/s11783-011-0353-z

Abstract: Thus, single and joint toxic effects of 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8- hexamethylcyclopenta-gamma

Keywords： 1     3     4     6     7     8-hexahydro-4     6     6     7     8     8-hexamethylcyclopenta-gamma-2-benzopyran (HHCB)     cadmium (Cd)     antioxidant    

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Genetic variants in the ADD1 and GNB3 genes and blood pressure response to potassium supplementation

Dai-Hai YU PhD, Jian-Feng HUANG MD, Ji-Chun CHEN MS, Jie CAO MS, Shu-Feng CHEN PhD, Dong-Feng GU MD,HIXSON PhD, Chung-Shiuan CHEN MS8, Paul K. WHELTON MD, MSc9,

Frontiers of Medicine 2010, Volume 4, Issue 1,   Pages 59-66 doi: 10.1007/s11684-010-0015-8

Abstract: We conducted a 7-day high-sodium intervention (307.8 mmol sodium/day) followed by a 7-day high-sodium

Keywords： blood pressure     genetics     polymorphism     die-tary potassium     potassium sensitivity     adducin 1 alpha (ADD1)     guanine nucleotide binding protein beta polypeptide 3 (GNB3)    

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Earthquakes in the north block of Tibet-Plateau and retrospect of prediction for Wenchuan M8.0 Earthquake

Men Kepei

Strategic Study of CAE 2009, Volume 11, Issue 6,   Pages 82-88

Abstract:

Since 1700, M≥7strong earthquakes have had an obvious commensurabilityprediction with Chinese characteristics, and conceive strong earthquake with magnitude 7 informationalBased on this, the 2008 Wenchuan M 8.0 great earthquake was predicted and M≥7 strong earthquakes willMeanwhile, the cause of formation about Wenchuan Earthquake has been discussed primarily.The results show that strong earthquake and strong earthquake chain can be predicted.

Keywords： the north block of Tibet Plateau     informational orderly network structure     the great Wenchuan Earthquake     strong earthquake prediction    

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Zeolitic imidazolate framework-8 (ZIF-8) for drug delivery: A critical review

Simin Feng, Xiaoli Zhang, Dunyun Shi, Zheng Wang

Frontiers of Chemical Science and Engineering 2021, Volume 15, Issue 2,   Pages 221-237 doi: 10.1007/s11705-020-1927-8

Abstract: Zeolitic imidazolate framework-8 (ZIF-8), composed of Zn ions and imidazolate ligands, is a class ofaspects ranging from synthesis methods, property characterization to potential applications of ZIF-8.This review focuses on the recent development of ZIF-8 synthesis methods and its promising applicationsThe potential risks of using ZIF-8 for drug delivery are also summarized.

Keywords： zeolitic imidazolate framework-8 (ZIF-8)     synthesis methods     applications     drug delivery    

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Analysis of Brucella cellular fatty acids

Zhen-Xiang ZHAO MS, Hai JIANG MD, Bu-Yun CUI MS, Hong-Yan ZHAO, Dong-Ri PIAO MS, Lan-Yu LI, Su-Zhen HAOMS,

Frontiers of Medicine 2010, Volume 4, Issue 2,   Pages 216-219 doi: 10.1007/s11684-010-0037-2

Abstract: showed that 19 reference strains were divided into five clusters: cluster 1 included (bv. 1, 2, 3, 5)and ; cluster 2 included (bv. 3, 4, 5, 6) and (bv. 1, 2, 3); cluster 3 included (bv. 1, 2, 7, 9)and ; cluster 4 was (bv. 4); and cluster 5 was .

Keywords： Brucella     gas chromatography     cellular fatty acids     dendrogram     typing    

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Preparation, identification, and clinical application of anti-HBs monoclonal antibody that binds both wild-type and immune escape mutant HBsAgs

Fanghe LI BM , Chunyan ZHANG MS , Jinghua LIU MS , Xiaoyan ZHANG MS , Bing YAN , Bo ZHANG MS , YongguoHUANG MS , Jingsong GONG BM , Yan CHEN BM ,

Frontiers of Medicine 2009, Volume 3, Issue 3,   Pages 277-283 doi: 10.1007/s11684-009-0047-0

Abstract: Using a standard cellular fusion technique and indirect enzyme-linked immunosorbent assay (ELISA), a hybridoma cell line strain secreting anti-HBs monoclonal antibody (mAb) (defined G6 mAb) was obtained. The cells grew and secreted mAb stably. Antibody titers in the culture supernatant and ascites were 2.048×10 and 4.096×10, respectively. By applying the anti-HBs G6 mAb and horseradish peroxidase (HRP)-labeled goat anti-HBs antibody, we developed a sandwich ELISA (defined G6m ELISA) for detecting both wild-type and immune escape mutant HBsAgs (IEM HBsAg). The assay was performed to detect 17 species of genome recombinant expression HBsAg, including two wild-type species and 15 IEM HBsAg species, which varied in the “a” determinant, in a group of patients infected with hepatitis B virus (HBV). The patients previously had a lower ELISA detection signal [(absorbance of patients/absorbance of normal people (P/N): 1.0―4.5)]. The results demonstrated that the sensitivity of this assay to wild-type HBsAg was no less than 0.125g/L; 12 of 15 IEM HBsAg species (P/N≥2.5) were positive for G6 mAb. Of the positive IEM HBsAg species, two had a low absorbance value at 450nm (), one had an intermediate value and nine had a high value, which was 7.55%(mean), 59.4% and 92.1%―109.4% of the wild-type value, respectively. The two species with low value and the three negative species mutated at the bases 120―124 in the first loop of the HBV “a” determinant. Using the G6 ELISA and two commercial ELISA kits (A and B), 177 patients were tested. The G6 ELISA had a significantly higher detection rate than either commercial ELISAs (19.21% 14.89% and 6.21%, respectively; <0.01, <0.05, respectively).

Keywords： hepatitis B virus     gene variation     hepatitis B surface antigen     immune escape     enzyme-linked immunosorbent assay    

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Study on factors affecting TB/HIV co-infection in four counties of China

Shi-Ming CHENG MD, Yu-Ji LAI MS, Er-Yong LIU MS, Lin ZHOU MD, Xue-Jing WANG MS, Qiu-Lan CHEN MS, Dong-MingLI MS, Ning WANG MD,

Frontiers of Medicine 2010, Volume 4, Issue 2,   Pages 185-191 doi: 10.1007/s11684-010-0040-7

Abstract: The factors affecting case detection of tuberculosis (TB)/human immunodeficiency virus (HIV) co-infection cases were explored in order to provide evidence-based formulation of a TB/HIV co-infection control strategy in China. Four counties with different modes of HIV transmission and varying cooperation mechanisms between TB and HIV institutions were selected. HIV test among TB patients and TB examination among people living with HIV/acquired immunodeficiency syndrome (AIDS) were conducted. Patients also completed questionnaires on potential factors affecting TB/HIV co-infection. The results showed that 19 (1.7%) were HIV-positive among 1089 cases of people living with active TB who received HIV testing. Conversely, there were 126 (10%) cases of active TB among 1255 cases of people living with HIV/AIDS. Among the newly discovered 145 cases of TB/HIV co-infection, AIDS institutions found 86.9% of these co-infections and 14.1% came from TB institutes. In different registration categories, there were 31 (21.4%) cases of smear positive TB, 104 (71.7%) cases of smear negative TB, and extrapulmonary cases accounted for 10 (6.9%). Gender, occupation, marital status, ethnic group, education, HIV transmission route, CD4 level, and type of TB susceptible symptoms had significant effects on whether HIV/AIDS patients were co-infected with TB disease (<0.01). Sex, age, ethnic group, occupation, and type of tuberculosis had no significant influence on whether TB patients had HIV infection. AIDS institutions could find more TB/HIV co-infection patients in comparison with TB institutions, particularly in patients with smear negative pulmonary tuberculosis and extrapulmonary tuberculosis. Therefore, a cooperation mechanism should be built up between TB and HIV control systems, and routine TB checks should be conducted for HIV/AIDS patients. In areas where sex or drug use is the major transmission mode of HIV infection, antiretroviral therapy should be expanded, treatment adherence should be improved and patients’ immunity level should be increased in order to decrease TB incidence. Cough and expectoration of more than two weeks, bloody sputum, and recurrent fevers could be revealing symptoms in TB screening of HIV/AIDS patients.

Keywords： tuberculosis/acquired immunodeficiency syndrome     dual infection     prevention and control     case detection     impact factors    

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Role of salivary matrix metalloproteinase-8 (MMP-8) in chronic periodontitis diagnosis

Namita Gupta,N.D. Gupta,Akash Gupta,Saif Khan,Neha Bansal

Frontiers of Medicine 2015, Volume 9, Issue 1,   Pages 72-76 doi: 10.1007/s11684-014-0347-x

Abstract: This study aimed to correlate salivary levels of MMP-8 and periodontal parameters of chronic periodontitisto establish MMP-8 as a noninvasive marker for the early diagnosis of chronic periodontitis.Around 3 ml of unstimulated and whole expectorated saliva was collected for MMP-8 estimation by ELISAusing Quantikine human total MMP-8 immunoassay kits.The MMP-8 levels and periodontal status (PPD, CAL, GI, and PI) of groups I and II showed positive and

Keywords： matrix metalloproteinase-8     chronic periodontitis     pocket probing depth     clinical attachment level     gingival    

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LC/MS/MS and radioisotope method combined for recognizing the affinity between catalpol and OCT2 transporter

Zhiyu ZHANG, Changxiao LIU, Duanyun SI, Rong LU, Xiulin YI

Frontiers of Chemical Science and Engineering 2012, Volume 6, Issue 4,   Pages 436-442 doi: 10.1007/s11705-012-1222-4

Abstract: In this paper, chromatography/tandem mass spectrometry (LC/MS/MS) combined with radioisotope method wasAnd samples were precipitated with methanol and quantified with LC/MS/MS.

Keywords： catalpol     LC/MS/MS     OCT2    

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Protective efficacy of vaccination with NcMIC3 and NcMIC8 against

Taotao ZHANG, Xiao ZHANG, Qun LIU, Jianhai XU, Jing LIU

Frontiers of Agricultural Science and Engineering 2019, Volume 6, Issue 2,   Pages 188-196 doi: 10.15302/J-FASE-2019253

Abstract: Several studies have indicated that MIC3 and MIC8 are important adhesion factors and potential vaccinestudy, we evaluated the protective efficacy of recombinant proteins and DNA vaccines of NcMIC3 and NcMIC8.BALB/c mice were immunized with rNcMIC3, rNcMIC8, pcDNA3.1-NcMIC3 and pcDNA3.1-NcMIC8 respectively, andIn addition, mice immunized with rNcMIC3 and rNcMIC8 a had lower parasite burden in brain tissue comparedThese results demonstrate that rNcMIC3 and rNcMIC8 could induce humoral and Th2-type immune response,

Keywords： NcMIC3     NcMIC8     Neospora caninum     vaccination    

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The Undersea Tunnel on Qingdao Metro Line 8

Weiguo He, Peng Liu

Engineering 2018, Volume 4, Issue 2,   Pages 167-169 doi: 10.1016/j.eng.2018.03.012

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A pooling strategy of a PCR-based assay to detect Angiostrongylus cantonensis in snail intermediate host, Pomacea canaliculata

Fu-Rong WEI MS, Shan LV PhD, He-Xiang LIU, Ling HU, Yi ZHANG MS,

Frontiers of Medicine 2010, Volume 4, Issue 2,   Pages 204-207 doi: 10.1007/s11684-010-0043-4

Abstract: Pooling field specimens could reduce the number of assay and thus increase the efficiency in detecting and screening pathogen infections by polymerase chain reaction (PCR)-based assay. We investigated a pooling strategy in diagnosis of in Two settings of specimens were prepared, divided into portions and detected by multiplex PCR. Specimens A was 0.4490 g positive lung tissue of 28 larval nodes from four snails mixed with 1.310€g negative lung tissue from six snails and divided into 32 portions. Specimens B was 0.5448 g positive lung tissue with 26 larval nodes from two snails mixed with 1.092 g negative lung tissue from seven snails and divided into 48 portions. Repeated sampling was performed and sample size-accumulated positive rate curves were drawn. According to the sample size-accumulated positive rate curves, the appropriate sample size of the two specimens were 18 and 15, respectively, which is 0.36–0.58 to the total sample size. These test characteristics and the relevant factors to the sample size would need to be determined in much larger studies and more appropriately in field populations. The result indicates that the number of larval node is not the most important, nor the only factor to the sample size. It also implies the feasibility to detect in by pooling strategies.

Keywords： Angiostrongylus cantonensis     Pomacea canaliculata     multiplex polymerase chain reaction     diagnosis     pooling    

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Development of 8-inch Key Processes for Insulated-Gate Bipolar Transistor Article

Guoyou Liu,Rongjun Ding,Haihui Luo

Engineering 2015, Volume 1, Issue 3,   Pages 361-366 doi: 10.15302/J-ENG-2015043

Abstract:

Based on the construction of the 8-inch fabrication line, advanced process technology of 8-inch wafergreat-leap forward technological development for the manufacturing of high-voltage IGBT from 6-inch to 8-

Keywords： insulated-gate bipolar transistor (IGBT)     high power density     trench gate     8-inch     rail transportation    

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The feasibility of accurate earthquake prediction by HRT wave and examples of strong earthquakes includingWenchuan Earthquake （M ＝8）

Zhao Yulin and Qian Fuye

Strategic Study of CAE 2009, Volume 11, Issue 6,   Pages 111-122

Abstract:

The method of earthquake short-term and impending prediction by usingnew, quantitative technology of simultaneous determination of the location, magnitude and time of an earthquake.Theearthquake preparation processes and precursor mechanism are considered as a "blackbox" .Using

Keywords： “black box”& HRT wave model     PS-100HRT instrument system     discovery of HRT wave precursor and its regularity     practicality of HRT wave model    

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Title Author Date Type Operation

The Physical Precursors for the Ms 8.7 and Ms 8.5 Earthquakes in Indian Ocean

Sun Wei,Sun Xiaoming

Journal Article

Single and joint effects of HHCB and cadmium on zebrafish (

Lei ZHANG, Jing AN, Qixing ZHOU

Journal Article

Genetic variants in the ADD1 and GNB3 genes and blood pressure response to potassium supplementation

Dai-Hai YU PhD, Jian-Feng HUANG MD, Ji-Chun CHEN MS, Jie CAO MS, Shu-Feng CHEN PhD, Dong-Feng GU MD,HIXSON PhD, Chung-Shiuan CHEN MS8, Paul K. WHELTON MD, MSc9,

Journal Article

Earthquakes in the north block of Tibet-Plateau and retrospect of prediction for Wenchuan M8.0 Earthquake

Men Kepei

Journal Article

Zeolitic imidazolate framework-8 (ZIF-8) for drug delivery: A critical review

Simin Feng, Xiaoli Zhang, Dunyun Shi, Zheng Wang

Journal Article

Analysis of Brucella cellular fatty acids

Zhen-Xiang ZHAO MS, Hai JIANG MD, Bu-Yun CUI MS, Hong-Yan ZHAO, Dong-Ri PIAO MS, Lan-Yu LI, Su-Zhen HAOMS,

Journal Article

Preparation, identification, and clinical application of anti-HBs monoclonal antibody that binds both wild-type and immune escape mutant HBsAgs

Fanghe LI BM , Chunyan ZHANG MS , Jinghua LIU MS , Xiaoyan ZHANG MS , Bing YAN , Bo ZHANG MS , YongguoHUANG MS , Jingsong GONG BM , Yan CHEN BM ,

Journal Article

Study on factors affecting TB/HIV co-infection in four counties of China

Shi-Ming CHENG MD, Yu-Ji LAI MS, Er-Yong LIU MS, Lin ZHOU MD, Xue-Jing WANG MS, Qiu-Lan CHEN MS, Dong-MingLI MS, Ning WANG MD,

Journal Article

Role of salivary matrix metalloproteinase-8 (MMP-8) in chronic periodontitis diagnosis

Namita Gupta,N.D. Gupta,Akash Gupta,Saif Khan,Neha Bansal

Journal Article

LC/MS/MS and radioisotope method combined for recognizing the affinity between catalpol and OCT2 transporter

Zhiyu ZHANG, Changxiao LIU, Duanyun SI, Rong LU, Xiulin YI

Journal Article

Protective efficacy of vaccination with NcMIC3 and NcMIC8 against

Taotao ZHANG, Xiao ZHANG, Qun LIU, Jianhai XU, Jing LIU

Journal Article

The Undersea Tunnel on Qingdao Metro Line 8

Weiguo He, Peng Liu

Journal Article

A pooling strategy of a PCR-based assay to detect Angiostrongylus cantonensis in snail intermediate host, Pomacea canaliculata

Fu-Rong WEI MS, Shan LV PhD, He-Xiang LIU, Ling HU, Yi ZHANG MS,

Journal Article

Development of 8-inch Key Processes for Insulated-Gate Bipolar Transistor

Guoyou Liu,Rongjun Ding,Haihui Luo

Journal Article

The feasibility of accurate earthquake prediction by HRT wave and examples of strong earthquakes includingWenchuan Earthquake （M ＝8）

Zhao Yulin and Qian Fuye

Journal Article